Moderate Monitor for an increase in sildenafil-related adverse reactions if coadministration with diltiazem is necessary; a dose reduction of sildenafil may be necessary when prescribed for erectile dysfunction. The AUC and Cmax for cinacalcet increased 2. I take Cardizem for high blood pressure, and lately I've had acne on my face. Take on an empty stomach. Drugs that inhibit CYP3A4 such as diltiazem may increase plasma concentrations of estrogens and cause estrogen-related side effects such as nausea and breast tenderness. Moderate The combination of diltiazem and a beta-blocker, like metoprolol, is usually well tolerated; the combination is often used for their combined therapeutic benefits to reduce angina and improve exercise tolerance. Chlorpheniramine; Hydrocodone: Read all information given to you. Coadministration may result in increased rilpivirine cartia concentrations. After the first fingolimod dose, overnight monitoring with cartia ECG in a medical facility is advised for patients who cannot stop taking drugs that slow the heart rate or atrioventricular conduction. Other medications may slow down metabolism or cause fluid retention. An ergot alkaloid dose reduction may be necessary if these drugs are used together. This interaction can be therapeutically advantageous, but dosages must be adjusted accordingly. If concomitant use is unavoidable, reduce the dose of olaparib tablets to mg twice daily; reduce the dose of olaparib capsules to mg twice daily. This information is for educational purposes only, and not meant to provide medical advice, treatment, or diagnosis. Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. This material is provided for cartia purposes only and is not intended for medical advice, diagnosis or treatment. Regards, cartia xt, Derek Dore, PharmD. Use Cartia XT diltiazem long-acting capsules as ordered by your doctor.
Drospirenone; Estradiol: Carbinoxamine; Carfia Pseudoephedrine: Major Avoid coadministration of cartia with diltiazem if possible due to increased plasma exposure of brigatinib; an increase in brigatinib-related adverse reactions may occur. Chlorpheniramine; Dextromethorphan; Phenylephrine: Concomitant use of diltiazem, a CYP3A4 inhibitor, and dihydroergotamine, a CYP3A4 substrate with a narrow therapeutic range, may result in increased ergot alkaloid levels. Ombitasvir; Paritaprevir; Ritonavir: Subsequent bolus doses should be individualized. Diltiazem should be used with extreme caution in xtt taking beta-adrenergic blocking agents. Blood pressure and heart rates should be monitored closely to confirm that the desired antihypertensive effect is achieved. Carbinoxamine; Pseudoephedrine: We comply with the HONcode standard for trustworthy health information - verify here. Moderate Olanzapine may induce orthostatic hypotension cartia thus enhance the effects of antihypertensive agents. In addition, itraconazole may increase diltiazem serum concentrations via inhibition of CYP3A4 with the potential for diltiazem toxicity. Carbinoxamine; Hydrocodone; Phenylephrine: Monitor blood pressure and fluid volume status closely in patients receiving conivaptan infusion.
Use Cartia XT diltiazem long-acting capsules as ordered by your doctor. These findings have cartoa observed when both drugs were given orally. Careful monitoring of blood pressure is suggested during concurrent therapy of MAOIs with calcium-channel blockers. It is generally recommended to avoid grapefruit juice during calcium-channel blocker therapy. Mefenamic Acid: Czrtia is recommended when administering these medications in combination. A variety of skin rashes and pustules have been reported in patients taking Cardizem xf. Major Due to the risk for serious colchicine toxicity including multi-organ failure and death, avoid coadministration of colchicine and diltiazem in patients with normal renal and cartia function unless cartia use of both agents is cartia. Additive reductions in blood pressure may be seen when fish oils are used in a patient already taking antihypertensive agents. If coadministration is necessary, patients should be counseled on measures to prevent orthostatic hypotension, crtia as sitting on the edge of the bed for several minutes prior to standing in the morning and rising slowly from a seated position. Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide: The capsule may be administered by opening the capsule and sprinkling the capsule contents onto a spoonful of applesauce, cartia xt. Dapagliflozin; Saxagliptin: If concurrent treatment with diltiazem is necessary, strongly consider dartia lapatinib dose reduction. Carbinoxamine; Hydrocodone; Pseudoephedrine: Major Avoid the concurrent use of cobimetinib with diltiazem therapy due to the risk of cobimetinib toxicity. Patients receiving amifostine at doses recommended for chemotherapy should have antihypertensive therapy interrupted 24 hours preceding administration of amifostine.
Moderate Ginseng appears to inhibit the metabolism of calcium-channel blockers, perhaps by inhibiting the CYP3A4 isoenzyme. If you are experiencing a slow heart rate, consult with your physician or cardiologist right away. Major Pasireotide may cause a decrease in heart rate. Ezetimibe; Simvastatin: Medically reviewed on Feb 6, Use this combination with caution in patients receiving bromocriptine for other indications. High Blood Pressure amlodipinelisinoprillosartanfurosemidehydrochlorothiazidemetoprololatenololLasixMore Dapagliflozin; Saxagliptin: Initially, 30 mg PO 4 times per day administered before meals and at bedtime, gradually increasing the dosage at 1- or 2-day intervals until angina is optimally controlled. Patients should be instructed to rise slowly from a sitting position, and to report syncope or changes in blood pressure or heart rate to their health care provider. Exercise caution when co-administering systemic azole antifungals and calcium-channel blockers. Moderate Although data are not available, CYP3A4 inhibitors, such as diltiazem, may decrease systemic clearance of eszopiclone leading to prolonged effects. You can also report them to the U. Food and Drug Administration by visiting www. Common side effects with diltiazem are hypotension abnormally low blood pressurebradycardia abnormally low heart beatheadache, fatigue, weakness, drowsiness, constipation or diarrhea, nausea, vomiting, facial flushing, and difficulty sleeping. Moderate Diltiazem is a CYP3A4 inhibitor and may reduce the metabolism of estazolam and increase the potential for benzodiazepine toxicity. Some antihypertensives require a gradual taper to avoid adverse consequences caused by abrupt discontinuation. Moderate Monitor for silodosin-related adverse effects if coadministered with diltiazem; silodosin exposure may be increased.
Cartia XT mg, orange, capsule. Lower initial doses or slower dose titration of risperidone may be necessary in patients receiving antihypertensive agents concomitantly. Diltiazem prevents the flow of calcium in muscle tissue to keep the blood vessels from narrowing, making it easier for the heart to pump blood through the body. We do not record any personal information entered above. If you think there has been an overdose, call your poison control center or get medical care right away. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. Moderate Phenylephrine's cardiovascular effects may reduce the antihypertensive effects of calcium-channel blockers. Cartia The combination of diltiazem and a beta-blocker, like penbutolol, cartia xt, is usually well tolerated; the combination is often used for their combined therapeutic benefits to reduce angina and improve exercise tolerance. If these drugs are co-administered, dose adjustment of repaglinide may be necessary. Minor Additive bradycardia may occur in patients receiving paclitaxel and other drugs known to cause bradycardia, such as calcium-channel blockers like diltiazem. Although drug interaction studies have not been conducted, the serum concentration of diltiazem may be increased with concomitant administration of indinavir. Moderate Coadministrator topiramate with diltiazem with caution. Ethinyl Estradiol; Norethindrone; Ferrous fumarate: Use caution with in-clinic dosing for erectile dysfunction ED and monitor for the effects on blood pressure. Diltiazem is a substrate and inhibitor of the hepatic isoenzyme CYP3A4; isavuconazole, the active moiety of isavuconazonium, is a sensitive substrate and moderate inhibitor of CYP3A4. If concurrent use of halofantrine and a CYP3A4 inhibitor is warranted, it would be prudent to use caution and monitor the ECG periodically.
Dapagliflozin; Saxagliptin: X and verapamil have potential to inhibit CYP3A4 metabolism of bosentan. If diltiazem is discontinued, the original encorafenib dose may be resumed after 3 to 5 elimination half-lives of diltiazem. Patients should be monitored for efficacy and cartia. Carbidopa; Levodopa: Red Yeast Rice: Drug Czrtia Rx. Close monitoring of blood pressure or the selection of alternative therapeutic agents may be cartia. Darunavir; Cobicistat: Do not start, stop, or change the dose of any drug without checking with your cartia. Carttia caution when co-administering systemic azole antifungals and carti blockers. Major Due to the risk for serious colchicine toxicity including multi-organ failure and death, cartia xt, avoid coadministration of colchicine and diltiazem in patients with normal renal and hepatic function unless the use of both agents is imperative. Donepezil; Memantine: If coadministration is necessary, monitor patients closely at frequent intervals and consider a dosage reduction of hydrocodone until stable drug effects are achieved. Diphenhydramine; Ibuprofen: It is theoretically possible that excessive doses of ginger could affect the action of inotropes; however, no clinical data are available. Monitor plasma PTH and serum calcium and phosphorous concentrations if a patient initiates or discontinues therapy with this combination. If coadministration in patients with normal renal and hepatic function cannot be avoided, adjust the dose of colchicine by either reducing the daily dose or the carita frequency, and carefully monitor for colchicine toxicity. After 15 minutes, a second bolus dose of 0. Hawthorn, Crataegus laevigata:
When an alternative therapy is not possible, patients should be monitored for the desired cardiovascular effects on heart rate, chest pain, or blood pressure, cartia xt, as well as associated rifabutin side effects. According to the manufacturer, patients receiving clozapine in combination with a CYP3A4 inhibitor should be monitored for adverse reactions. The mechanism of this interaction is unclear. Diltiazem can inhibit colchicine's metabolism cartia CYP3A4, resulting in increased colchicine exposure. Diltia XT mg, gray, capsule. Any time you experience swelling, you should consult with your doctor to rule out any serious medical conditions. Diltiazem should not be used in advanced aortic stenosis because it can cause a worsening of the abnormal pressure gradient associated with this condition. In addition, orthostatic vital signs should be monitored in patients who are at risk for hypotension, such as those receiving cariprazine in combination with antihypertensive agents. Diltiazem ER, in most situations, cartia xt, should be swallowed whole and not chewed or crushed. Chlorthalidone; Clonidine: Nevertheless, cartia combinations should be used cautiously, and close monitoring of serum digoxin concentrations is essential to avoid enhanced toxicity. Moderate Concomitant use of isavuconazonium with diltiazem cartia result in increased serum concentrations of both drugs. Periodic evaluation of blood pressure is advisable during concurrent use of dexmethylphenidate and antihypertensive agents, particularly during initial coadministration cartia after dosage increases of dexmethylphenidate. These are not all of the side effects that may occur. Moderate Monitor for an increase in maraviroc adverse effects with concomitant use of diltiazem due to a possible increase in maraviroc exposure. If concurrent use of asenapine and antihypertensive agents is necessary, patients should be counseled on measures to prevent orthostatic hypotension, such as sitting on the edge of the bed for several minutes prior to standing in the morning and rising slowly from a seated position. This slow heart beat can cause fatigue and other symptoms. Should I be taking a calcium supplement? It should be taken with a full glass of water, either with or without food. Experience with fingolimod in patients receiving concurrent therapy with drugs that slow the heart rate or atrioventricular conduction is limited. Carbinoxamine; Hydrocodone; Phenylephrine:
Dextromethorphan; Diphenhydramine; Phenylephrine: I have high blood pressure, take diltiazem ER, and feel tired a lot. Photosensitizing agents: Major Decrease the acalabrutinib dose to mg PO once daily if coadministered with diltiazem. Diltiazem ER is also used to manage angina chest pain. Angina Pectoris Prophylaxis aspirin , metoprolol , diltiazem , atenolol , nitroglycerin , nifedipine , isosorbide mononitrate , More Diltiazem 90 mg-WAT, blue, oblong,. As diltiazem is both a substrate and an inhibitor of CYP3A4, monitor patients for corticosteroid-related side effects if prednisolone and diltiazem are taken. Moderate Paliperidone may cause orthostatic hypotension, thereby enhancing the hypotensive effects of antihypertensive agents. It is theoretically possible that excessive doses of ginger could affect the action of inotropes; however, no clinical data are available. Following hawthorn administration, the cardiac action potential duration is increased and the refractory period is prolonged. If use together is necessary, obtain an ECG prior to lacosamide initiation and after treatment has been titrated to steady-state. Major Alfuzosin and diltiazem may have additive vasodilatory actions; concurrent use of these agents can result in hypotension. Moderate Monitor for a decrease in the efficacy of ifosfamide if coadministration with diltiazem is necessary. Although concomitant use of moderate CYP3A4 inhibitors with lomitapide has not been studied, a significant increase in lomitapide exposure is likely during concurrent use. Diltiazem may increase plasma concentrations of quetiapine through CYP3A4 inhibition. Patients who choose to take CoQ10 concurrently with antihypertensive medications should receive periodic blood pressure monitoring. Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Brompheniramine; Guaifenesin; Hydrocodone: Concurrent use of amiodarone and diltiazem may result in bradycardia and depressed cardiac output; monitor clinical response. Diltiazem 90 mg-MYL, white, oblong, film coated. You may also report side effects at http: According to the OBRA guidelines, antihypertensive regimens should be individualized to achieve the desired outcome while minimizing adverse effects. Co-Enzyme Q10, Ubiquinone: This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Moderate Concurrent administration of antihypertensive agents could lead to additive hypotension when administered with milrinone. Lumacaftor; ivacaftor may reduce the efficacy of diltiazem by decreasing its systemic exposure. Print this page Add to My Med List. The brand cartia is no longer marketed in the United States; however, generic equivalents are available.
Major The vasoconstricting actions of oxymetazoline, an alpha adrenergic agonist, may reduce the antihypertensive effects produced by calcium-channel blockers. Amlodipine; Olmesartan: Nebivolol; Valsartan: Drug information contained herein may be time sensitive. Systemic concentrations of eletriptan may be increased. Oxycodone is a CYP3A4 substrate, and coadministration with a moderate inhibitor like diltiazem can increase oxycodone exposure resulting in increased or prolonged opioid effects including fatal respiratory depression, particularly when an inhibitor is added to a stable dose of oxycodone. The mean dosage range was 90 to mg PO twice daily. During coadministration with diltiazem, close monitoring is suggested, with adjustment of buspirone dosage if needed. Based on the pharmacology of conivaptan, there is also potential for additive hypotensive effects when coadministered with calcium-channel blockers. We comply with the HONcode standard for trustworthy health information - verify here. Major Avoid concomitant use of bosutinib and diltiazem as bosutinib plasma exposure may be significantly increased resulting in an increased risk of bosutinib adverse events e. In patients who are also receiving treatment with cyclosporine, the magnitude of this interaction may be amplified. Minor Estrogen containing oral contraceptives can induce fluid retention and may increase blood pressure in some patients. If not possible, closely monitor for increased side effects of doxorubicin including myelosuppression and cardiotoxicity. It may be prudent to avoid melatonin use during calcium-channel blocker therapy. Aliskiren; Amlodipine: The usual dosage range during clinical studies was to mg PO twice daily. Angina Pectoris Prophylaxis aspirin , metoprolol , diltiazem , atenolol , nitroglycerin , nifedipine , isosorbide mononitrate , More Teva's generic medications are available in most pharmacies across the United States, though not all pharmacies carry the same Teva medications. Guaifenesin; Hydrocodone: The applesauce mixture should be swallowed immediately, and then followed cartia a glass of water. Moderate Monitor blood pressure and heart rate if coadministration of diltiazem with cobicistat is necessary. Acetaminophen; Butalbital; Caffeine; Codeine: This is not a list of all drugs or health problems that interact with Cartia XT diltiazem long-acting capsules. I take Diltiazem ER mg capsule, twice a day. Diltiazem 60 mg-TEV, orange, round.